Open Protocols

Protocol Name	Investigatory Role	Biomarkers	Data Collections
LTP2 Results Analysis-Showe-Wistar-2024	Leading	0	0

Closed Protocols

This person has no closed protocols at the present moment.

Publications

Publication Name	PubMed ID	Journal
A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT.	30487137	Cancer Res
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay.	28436945	Nat Struct Mol Biol
BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.	27803105	Cancer Res
Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus.	32054837	Nat Commun
Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization.	31831736	Nat Commun
Long non-coding RNAs in metastasis.	29230620	Cancer Metastasis Rev
N<sup>6</sup>-Methylation of Adenosine of <i>FZD10</i> mRNA Contributes to PARP Inhibitor Resistance.	30967398	Cancer Res
Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition.	28747513	Sci Transl Med
Structural and functional analysis of the human POT1-TPP1 telomeric complex.	28393830	Nat Commun
TIGIT and Helios Are Highly Expressed on CD4<sup>+</sup> T Cells in Sézary Syndrome Patients.	27592800	J Invest Dermatol
Transgenic Expression of the Mitochondrial Chaperone TNFR-associated Protein 1 (TRAP1) Accelerates Prostate Cancer Development.	27754870	J Biol Chem

Interests

lung cancer

Development of a gene expression signature from whole blood samples collected in PAXgene tubes for the early detection of NSCLC.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Site

Wistar

Degree(s)

Ph.D.

Email

lshowe@wistar.org

Fax

215-495-6812

Person ID

3682

EDRN Title

EDRN Associate Member

Note

To update contact information, please visit the Data Management and Coordinating Center .