AKR1C2
- Aliases
-
- 3-alpha-HSD3
- AKR1C-pseudo
- AKR1C2
- BABP
- Chlordecone reductase homolog HAKRD
- DD
- DD-2
- DD/BABP
- DD2
- DDH2
- Dihydrodiol dehydrogenase 2
- Dihydrodiol dehydrogenase/bile acid-binding protein
- HAKRD
- HBAB
- MCDR2
- SRXY8
- Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
- Type III 3-alpha-hydroxysteroid dehydrogenase
- aldo-keto reductase family 1 member C2
- aldo-keto reductase family 1, member C2
- aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
- chlordecone reductase homolog HAKRD
- dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase
- dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III
- pseudo-chlordecone reductase
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
- type II dihydrodiol dehydrogenase
- type III
- Description
- From NCBI Gene: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- AKR1C2
- Certifications
-
- None
- QA State for Breast
- Curated
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.