ANO1
- Aliases
-
- ANO1
- DOG1
- Discovered on gastrointestinal stromal tumors protein 1
- FLJ10261
- ORAOV2
- Oral cancer overexpressed protein 2
- TAOS2
- TMEM16A
- Transmembrane protein 16A
- Tumor-amplified and overexpressed sequence 2
- anoctamin 1, calcium activated chloride channel
- anoctamin-1
- discovered on gastrointestinal stromal tumors protein 1
- oral cancer overexpressed 2
- transmembrane protein 16A
- transmembrane protein 16A (eight membrane-spanning domains)
- tumor-amplified and overexpressed sequence 2
- Description
- ANO1, or anoctamin-1, is a calcium-activated chloride channel gene overexpressed in many tumors. ANO1 is ubiquitously expressed in epithelia and is thought to be important in epithelial fluid transport.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- ANO1
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.