ARHGEF16
- Aliases
-
- ARHGEF16
- EPHEXIN4
- Ephexin-4
- GEF16
- NBR
- Rho guanine exchange factor (GEF) 16
- Rho guanine nucleotide exchange factor (GEF) 16
- ephexin-4
- rho guanine nucleotide exchange factor 16
- Description
- ARHGEF16 is a guanine nucleotide exchange factor. Guanine nucleotide exchange factors regulate the activation of Rho-like GTPases. Guanidine exchange factors promote the GTP activation of Rho GTPase's by catalyzing the exchange of GDP for GTP.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- ARHGEF16
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
- The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.