Aliases

• 16A
• ATP6AP1
• ATP6IP1
• ATP6S1
• ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1
• ATPase, H+ transporting, lysosomal accessory protein 1
• ATPase, H+ transporting, lysosomal interacting protein 1
• Ac45
• CF2
• H-ATPase subunit
• ORF
• Protein XAP-3
• V-ATPase Ac45 subunit
• V-ATPase S1 accessory protein
• V-ATPase subunit S1
• V-type proton ATPase subunit S1
• VATPS1
• Vacuolar proton pump subunit S1
• XAP-3
• XAP3

Description

From NCBI Gene: This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]

Attributes

QA State

Under Review

Type

Protein

HGNC Name

ATP6AP1