CD74
- Aliases
-
- CD74
- CD74 Antigen
- CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated)
- CD74 Molecule
- CD74 Molecule, Major Histocompatibility Complex, Class II Invariant Chain
- DHLAG
- Gamma Chain Of Class II Antigens
- HLA Class II Histocompatibility Antigen Gamma Chain
- HLA-DR Antigens-Associated Invariant Chain
- HLA-DR-Gamma
- HLADG
- II
- Ia Antigen-Associated Invariant Chain
- Ia-Associated Invariant Chain
- Ia-GAMMA
- Ii
- MHC HLA-DR Gamma Chain
- P33
- Description
- From NCBI Gene: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- CD74
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.