Aliases

• CGA
• CHGA
• CgA
• Pituitary secretory protein I
• SP-I
• betagranin (N-terminal fragment of chromogranin A)
• chromogranin A (parathyroid secretory protein 1)
• chromogranin-A
• pancreastatin
• parastatin
• parathyroid secretory protein 1
• pituitary secretory protein I
• vasostatin

Description

From NCBI Gene: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Attributes

QA State

Under Review

Type

Protein

HGNC Name

CHGA