Aliases

• CREB regulated transcription coactivator 3
• CREB-regulated transcription coactivator 3
• CRTC3
• FLJ21868
• TORC-3
• TORC3
• Transducer of CREB protein 3
• Transducer of regulated cAMP response element-binding protein 3
• transducer of regulated CREB protein 3
• transducer of regulated cAMP response element-binding protein (CREB) 3
• transducer of regulated cAMP response element-binding protein 3

Description

From NCBI Gene: This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

CRTC3