DLD

Aliases
  • DLD
  • DLDD
  • DLDH
  • Diaphorase
  • Dihydrolipoamide Dehydrogenase
  • Dihydrolipoamide Dehydrogenase (E3 Component Of Pyruvate Dehydrogenase Complex, 2-Oxo-Glutarate Complex, Branched Chain Keto Acid Dehydrogenase Complex)
  • Dihydrolipoyl Dehydrogenase, Mitochondrial
  • E3
  • E3 Component Of Pyruvate Dehydrogenase Complex, 2-Oxo-Glutarate Complex, Branched Chain Keto Acid Dehydrogenase Complex
  • Epididymis Secretory Sperm Binding Protein
  • Glycine Cleavage System L Protein
  • Glycine Cleavage System Protein L
  • LAD
  • Lipoamide Dehydrogenase
  • Lipoamide Reductase
  • Lipoyl Dehydrogenase
  • OGDC-E3
  • PHE3
Description
From NCBI Gene: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Attributes
QA State
Under Review
Type
Protein
HGNC Name
DLD
Certifications
  • None
QA State for Breast
Under Review

 Non-Public Biomarker

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 Non-Public Biomarker

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 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.