ENPP2
- Aliases
-
- ATX
- ATX-X
- AUTOTAXIN
- Autotaxin
- Autotaxin-T
- E-NPP 2
- ENPP2
- Ectonucleotide Pyrophosphatase/Phosphodiesterase 2
- Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2
- Extracellular Lysophospholipase D
- LysoPLD
- NPP2
- PD-IALPHA
- PDNP2
- Phosphodiesterase I/Nucleotide Pyrophosphatase 2
- Plasma Lysophospholipase D
- Description
- From NCBI Gene: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- ENPP2
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.