ERCC4

Aliases
  • DNA excision repair protein ERCC-4
  • DNA repair endonuclease XPF
  • DNA repair protein complementing XP-F cells
  • EC 3.1.-.-
  • ERCC11
  • ERCC4
  • RAD1
  • XPF
  • Xeroderma pigmentosum group F-complementing protein
  • excision repair cross-complementing rodent repair deficiency, complementation group 4
  • excision-repair, complementing defective, in Chinese hamster
  • xeroderma pigmentosum group F-complementing protein
  • xeroderma pigmentosum, complementation group F
Description
ERCC4 is a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. It forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. Mutations in the ERCC4 gene can cause xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
Attributes
QA State
Under Review
Type
Gene
HGNC Name
ERCC4
Certifications
  • None
QA State for Lung
Under Review

 Non-Public Biomarker

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 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.