FERMT2
- Aliases
-
- FERMT2
- KIND2
- Kindlin-2
- MIG-2
- MIG2
- Mitogen-inducible gene 2 protein
- PH domain-containing family C member 1
- PLEKHC1
- Pleckstrin homology domain-containing family C member 1
- UNC112
- UNC112B
- fermitin family homolog 2
- fermitin family homolog 2 (Drosophila)
- fermitin family member 2
- kindlin 2
- kindlin-2
- mig-2
- mitogen inducible gene 2 protein
- mitogen-inducible gene 2 protein
- pleckstrin homology domain containing, family C (with FERM domain) member 1
- pleckstrin homology domain containing, family C member 1
- pleckstrin homology domain-containing family C member 1
- Description
- From NCBI Gene: Enables several functions, including actin binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell differentiation; and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol; focal adhesion; and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia. [provided by Alliance of Genome Resources, Nov 2021]
Attributes
- QA State
- Under Review
- Type
- Gene
- HGNC Name
- FERMT2
- Certifications
-
- None
- QA State for Prostate
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.