Aliases

• ATP-dependent DNA helicase VIII
• EC 3.6.4.12,EC 3.6.4.13
• G3BP
• G3BP-1
• G3BP1
• GAP SH3 domain-binding protein 1
• GAP binding protein
• GTPase activating protein (SH3 domain) binding protein 1
• HDH-VIII
• Ras-GTPase-activating protein SH3-domain-binding protein
• RasGAP-associated endoribonuclease G3BP
• hDH VIII
• ras GTPase-activating protein-binding protein 1

Description

From NCBI Gene: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

G3BP1