GCLM

Aliases
  • GCLM
  • GCS light chain
  • GLCLR
  • GSC light chain
  • Gamma-ECS regulatory subunit
  • Gamma-glutamylcysteine synthetase regulatory subunit
  • Glutamate--cysteine ligase modifier subunit
  • gamma-ECS regulatory subunit
  • gamma-glutamylcysteine synthetase
  • gamma-glutamylcysteine synthetase regulatory subunit
  • glutamate--cysteine ligase modifier subunit
  • glutamate--cysteine ligase regulatory subunit
  • glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)
  • glutamate-cysteine ligase modifier subunit delta2 alternative splicing
  • glutamate-cysteine ligase regulatory protein
  • glutamate-cysteine ligase, modifier subunit
Description
From NCBI Gene: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Attributes
QA State
Under Review
Type
Protein
HGNC Name
GCLM
Certifications
  • None
QA State for Breast
Curated

 Non-Public Biomarker

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 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.