GSTZ1
- Aliases
-
- EC 2.5.1.18
- EC 5.2.1.2
- GSTZ1
- GSTZ1-1
- Glutathione S-transferase zeta 1
- MAAI
- MAI
- S-(hydroxyalkyl)glutathione lyase
- glutathione S-alkyltransferase
- glutathione S-aralkyltransferase
- glutathione S-aryltransferase
- glutathione s-transferase Zeta 1
- glutathione transferase zeta 1
- maleylacetoacetate isomerase
- maleylacetone isomerase
- Description
- The GSTZ1 gene product, glutathione transferase zeta 1, is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is also involved in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.
Attributes
- QA State
- Under Review
- Type
- Gene
- HGNC Name
- GSTZ1
- Certifications
-
- None
- QA State for Lung
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.