Aliases

• DJ221C16.3
• H2B Clustered Histone 4
• H2B Histone Family, Member L
• H2B.1
• H2B/A
• H2B/G
• H2B/H
• H2B/K
• H2B/L
• H2BC10
• H2BC4
• H2BC6
• H2BC7
• H2BC8
• H2BFA
• H2BFG
• H2BFH
• H2BFK
• H2BFL
• HIST1H2BC
• HIST1H2BE
• HIST1H2BF
• HIST1H2BG
• HIST1H2BI
• Histone 1, H2bc
• Histone Cluster 1 H2B Family Member C
• Histone Cluster 1, H2bc
• Histone H2B Type 1-C/E/F/G/I
• Histone H2B.1 A
• Histone H2B.A
• Histone H2B.G
• Histone H2B.H
• Histone H2B.K
• Histone H2B.L

Description

This gene was formerly known as HIST1H2BC. From NCBI Gene: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. This transcript variant lacks a polyA tail but instead contains a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Apr 2020]

Attributes

QA State

Curated

Type

Gene

HGNC Name

H2BC4