HSPB8
- Aliases
-
- Alpha-crystallin C chain
- CMT2L
- CRYAC
- DHMN2
- E2-induced gene 1 protein
- E2IG1
- H11
- HMN2
- HMN2A
- HSP22
- HSPB8
- HspB8
- Protein kinase H11
- Small stress protein-like protein HSP22
- alpha-crystallin C chain
- heat shock 22kDa protein 8
- heat shock 27kDa protein 8
- heat shock protein beta-8
- protein kinase H11
- small stress protein-like protein HSP22
- Description
- From NCBI Gene: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Attributes
- QA State
- Curated
- Type
- Gene
- HGNC Name
- HSPB8
- Certifications
-
- None
- QA State for Prostate
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.