IMPDH2
- Aliases
-
- EC 1.1.1.205
- IMP (inosine 5'-monophosphate) dehydrogenase 2
- IMP (inosine monophosphate) dehydrogenase 2
- IMP dehydrogenase 2
- IMP oxireductase 2
- IMPD 2
- IMPD2
- IMPDH
- IMPDH 2
- IMPDH-II
- IMPDH2
- inosine 5' phosphate dehydrogenase 2
- inosine monophosphate dehydrogenase type II
- inosine-5'-monophosphate dehydrogenase 2
- Description
- The enzyme IMPDH2 catalyzes the rate-limiting step of conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed step in the de novo synthesis of guanine nucleotides. Therefore IMPDH2 is involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It is also thought to be involvedmin the development of malignancy and the growth progression of some tumors.
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- IMPDH2
- Certifications
-
- None
- QA State for Lung
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.