MIR21
- Aliases
-
- MIR21
- MIRN21
- hsa-mir-21
- miR-21
- miRNA21
- microRNA 21
- mir-21
- Description
- From NCBI Gene: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. miRNAs bind to complementary sequences in the 3' UTR of multiple target mRNAs, usually silencing the targeted mRNA. miRNAs may trigger the cleavage of their target molecules or act as translational repressors. miRNAs are thought to target approximatley 60% of all genes and are able to repress hundreds of targets each.
Attributes
- QA State
- Curated
- Type
- Genomic
- HGNC Name
- MIR21
- Certifications
-
- None
- QA State for Lung
- Curated
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer.
- Lung cancer signatures in plasma based on proteome profiling of mouse tumor models.
- Plasma microRNAs as potential biomarkers for non-small-cell lung cancer.
- The state of molecular biomarkers for the early detection of lung cancer.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.