PSMB1

Aliases
  • HC5
  • Macropain Subunit C5
  • Multicatalytic Endopeptidase Complex Subunit C5
  • PMSB1
  • PSC5
  • PSMB1
  • Proteasome (Prosome, Macropain) Subunit, Beta Type, 1
  • Proteasome 20S Subunit Beta 1
  • Proteasome Beta 1 Subunit
  • Proteasome Component C5
  • Proteasome Gamma Chain
  • Proteasome Subunit Beta 1
  • Proteasome Subunit Beta Type-1
  • Proteasome Subunit Beta6
  • Proteasome Subunit HC5
  • Proteasome Subunit Β6
  • Testicular Secretory Protein Li 45
Description
From NCBI Gene: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]
Attributes
QA State
Under Review
Type
Protein
HGNC Name
PSMB1
Certifications
  • None
QA State for Breast
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.