PTPA
- Aliases
-
- EC 5.2.1.8
- PP2A
- PP2A phosphatase activator
- PP2A subunit B' isoform PR53
- PP2A, subunit B', PR53 isoform
- PPP2R4
- PR53
- PTPA
- Phosphotyrosyl phosphatase activator
- Serine/threonine-protein phosphatase 2A regulatory subunit 4
- Serine/threonine-protein phosphatase 2A regulatory subunit B'
- phosphotyrosyl phosphatase activator
- protein phosphatase 2A activator, regulatory subunit 4
- protein phosphatase 2A, regulatory subunit B' (PR 53)
- serine/threonine-protein phosphatase 2A activator
- serine/threonine-protein phosphatase 2A regulatory subunit B'
- Description
- From NCBI Gene: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- PTPA
- Certifications
-
- None
- QA State for Breast
- Curated
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.