PTPMT1
- Aliases
-
- DUSP23
- EC 3.1.3.16,EC 3.1.3.48
- MOSP
- NB4 apoptosis/differentiation related protein
- PLIP
- PTEN-like phosphatase
- PTPMT1
- Phosphoinositide lipid phosphatase
- phosphoinositide lipid phosphatase
- protein tyrosine phosphatase, mitochondrial 1
- protein-tyrosine phosphatase mitochondrial 1
- Description
- PTPMT1 is a lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- PTPMT1
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.