Aliases

• 47 KDa Heat Shock Protein
• Arsenic-Transactivated Protein 3
• AsTP3
• CBP1
• CBP2
• Cell Proliferation-Inducing Gene 14 Protein
• Collagen-Binding Protein
• Colligin
• HSP47
• OI10
• PPROM
• RA-A47
• Rheumatoid Arthritis Antigen A-47
• Rheumatoid Arthritis-Related Antigen RA-A47
• SERPINH1
• SERPINH2
• Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1)
• Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 2
• Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 2, (Collagen-Binding Protein 2)
• Serpin H1
• Serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1)
• colligin-1
• colligin-2
• gp46

Description

From NCBI Gene: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]

Attributes

QA State

Under Review

Type

Protein

HGNC Name

SERPINH1