Aliases

• 18 kDa pulmonary-surfactant protein
• 6 kDa protein
• PSP-B
• Pulmonary surfactant-associated proteolipid SPL(Phe)
• SFTB3
• SFTP3
• SFTPB
• SMDP1
• SP-B
• pulmonary surfactant-associated protein B
• pulmonary surfactant-associated proteolipid SPL(Phe)
• surfactant protein B
• surfactant, pulmonary-associated protein B

Description

SFTPB, or pulmonary-associated surfactant protein B, is an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. These proteins are composed of 90% lipids and 10% proteins, and include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. There are several alternatively spliced transcript variants for this gene, all encoding the same protein.

Attributes

QA State

Under Review

Type

Protein

HGNC Name

SFTPB