ST14
- Aliases
-
- EC 3.4.21
- EC 3.4.21.109
- HAI
- MT-SP1
- MTSP1
- Matriptase
- Membrane-type serine protease 1
- OTTHUMP00000230931
- OTTHUMP00000230932
- PRSS14
- Prostamin
- Q9Y5Y6
- SNC19
- ST14
- Serine protease 14
- Serine protease TADG-15
- TADG15
- TMPRSS14
- Tumor-associated differentially-expressed gene 15 protein
- prostamin
- suppression of tumorigenicity 14 (colon carcinoma)
- suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
- suppressor of tumorigenicity 14 protein
- tumor associated differentially expressed gene 15 protein
- Description
- From NCBI Gene: The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008]
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- ST14
- Certifications
-
- None
- QA State for Ovary
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Certifications
-
- None
- QA State for Prostate
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.