Aliases

• EC 1.16.1.-
• FLJ23153
• STAMP2
• STEAP family member 4
• STEAP4
• Six-transmembrane epithelial antigen of prostate 4
• SixTransMembrane protein of prostate 2
• TIARP
• TNFAIP9
• Tumor necrosis factor, alpha-induced protein 9
• metalloreductase STEAP4
• six transmembrane prostate protein 2
• six-transmembrane epithelial antigen of prostate 4
• sixTransMembrane protein of prostate 2
• tumor necrosis factor, alpha-induced protein 9
• tumor necrosis-alpha-induced adipose-related protein

Description

From NCBI Gene: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

STEAP4