Aliases

• 60S ribosomal protein L40
• CEP52
• HUBCEP52
• L40
• MGC126879
• MGC126881
• MGC57125
• RPL40
• UBA52
• UBCEP2
• ubiquitin A-52 residue ribosomal protein fusion product 1
• ubiquitin carboxyl extension protein 52
• ubiquitin-52 amino acid fusion protein
• ubiquitin-60S ribosomal protein L40
• ubiquitin-CEP52

Description

Ubiquitin, one of the most highly conserved proteins, is coded for by a family of genes whose translation products give rise to several different proteins. There are four genes that code for ubiquitin: UBB, UBC, RPS27A, and UBA52. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. UBA52 and RPS27A genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains. This gene, UBA52, encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome.

Attributes

QA State

Under Review

Type

Protein

HGNC Name

UBA52