UBE2D2
- Aliases
-
- E2(17)KB2
- EC 6.3.2.19
- PUBC1
- UBC4
- UBC4/5
- UBC5B
- UBCH4
- UBCH5B
- UBE2D2
- UbcH5B
- Ubiquitin carrier protein D2
- Ubiquitin-conjugating enzyme E2(17)KB 2
- Ubiquitin-conjugating enzyme E2-17 kDa 2
- Ubiquitin-protein ligase D2
- ubiquitin carrier protein D2
- ubiquitin-conjugating enzyme E2 D2
- ubiquitin-conjugating enzyme E2(17)KB 2
- ubiquitin-conjugating enzyme E2-17 kDa 2
- ubiquitin-conjugating enzyme E2D 2
- ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
- ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5)
- ubiquitin-protein ligase D2
- Description
- From NCBI Gene: Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Attributes
- QA State
- Under Review
- Type
- Gene
- HGNC Name
- UBE2D2
- Certifications
-
- None
- QA State for Prostate
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.