Abbreviated Name

GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysp

Lead Investigator

Stoffel, Elena — University of Michigan

Coordinating Investigator

No coordinating investigator

Involved Investigators

• Stoffel, Elena — University of Michigan
• Costa, Jose — Yale University School of Medicine
• Chia (Retired), David — University of California Los Angeles

Abstract

No abstract availalbe.

Aims

Establish the feasibility of measuring the biomarkers in a multi-center clinical trial. 1.2   Estimate the variance of the biomarkers in cohorts defined by sex, race, age and histologic diagnosis (Barrett's intestinal metaplasia, Barrett's intestinal dysplasia [low-grade or high-grade], Adenocarcinoma, and non-Barrett’s controls). 1.3   Determine if the distributions of the biomarkers differ significantly among patients with different histologic diagnoses.

Analytic Method

No analytic method available.

Comments

No comments available.

Outcome

No outcome available.

Secure Outcome

No secure outcome available.

Publications

• No publications available at this time for this protocol.

Biomarkers

• No biomarkers available at this time for this protocol.

Data Collections

• No data collections available at this time for this protocol.

Finish Date

Jan 15 2009

Protocol ID

107

Protocol Type

Collaboration

Fields of Research

• Glycomics
• Hypermethylation
• Metabolomics
• Proteomics

Collaborative Group

G.I. and Other Associated Cancers Research Group

Cancer Types

• Malignant neoplasm of esophagus