Abbreviated Name

PASS Ref Set App: Catalona - Germline Variants

Lead Investigator

Lin UW, Daniel W. — University of Washington

Coordinating Investigator

Zheng, Yingye — Fred Hutchinson Cancer Center

Involved Investigators

• Lin UW, Daniel W. — University of Washington

Abstract

No abstract availalbe.

Aims

Specific Aim 1: Designing custom content array and genotyping We will work closely with all collaborators and CIDR to incorporate the 10,000 custom content variants specific to PC on the Illumina Infinium Multi-Ethnic Array. All 5061 DNA samples from men with PC on AS will be sent to CIDR for genotyping. Specific Aim 2: Testing previously reported variants Here, we will test the association between AS and variants previously associated with PC susceptibility or aggressiveness from the literature, study collaborators, and other colleagues. Specific Aim 3: Evaluating associations with new variants In this aim we will test the associations between the genome-wide variants and AS.

Analytic Method

No analytic method available.

Publications

• No publications available at this time for this protocol.

Biomarkers

• No biomarkers available at this time for this protocol.

Data Collections

• No data collections available at this time for this protocol.

 Team Project

Start Date

Feb 26 2018

Finish Date

Dec 31 2021

Protocol ID

433

Protocol Type

Single

Fields of Research

• Genomics

Collaborative Group

Prostate and Urologic Cancers Research Group

Cancer Types

• Malignant neoplasm of prostate

Phased Status

2