Fact or Myth? Black Patients Do Not Want to Participate in Clinical Trials.

Abstract

To assess strategies for optimizing participation of underserved minorities in a blood-based early colorectal cancer detection test study (PREEMPT CRC; NCT04369053) at a hospital serving primarily Black individuals.

Culturally sensitive, racially congruent research staff approached individuals undergoing average-risk screening colonoscopy. Consent/study procedures were synchronized with clinical appointments. Enrolled and not-enrolled patient characteristics were compared. Recruitment was compared with other study sites.

In total, 247 of 509 eligible individuals were enrolled; most were identified as Black (88.7%). No baseline characteristics were associated with participation. Recruitment was high compared with other sites (11th centile).

Recruitment barriers for Black individuals can be overcome when easy, culturally sensitive access is facilitated.

EDRN PI Authors
Medline Author List
  • Adelman RM
  • Baldo L
  • Ekpo E
  • Figueroa F
  • Knight R
  • Lee LC
  • Levin T
  • Liu JJ
  • Mills K
  • Pemu P
  • Shaukat A
  • Wang S
  • Xu C
PubMed ID
Appears In
Clin Transl Gastroenterol, 2025 Apr (issue 4)