COVID-19 Infection Before or After Colorectal Cancer Diagnosis Is an Independent Predictor of Mortality and Treatment Delays Compared to Patients Who Never Tested Positive.
Abstract
Given COVID-19's emergence as a new entity and colorectal cancer's (CRC) rising incidence in certain populations, we conducted this retrospective cohort study to determine the link between COVID-19 and the mortality of those with CRC and how socioeconomic factors influence it.
Using the National Cancer Database (NCDB), we used logistic regression to get the odds ratio (OR) for delayed treatment and Cox proportional hazards modeling for each stage to get the adjusted hazard ratios (HR) of mortality.
COVID-19 positivity was associated with higher mortality and delayed treatment. The association of race, ethnicity, insurance, urbanization, comorbidity burden, education levels, and income varied by when the patient tested positive relative to colorectal cancer diagnosis.
This implies that vaccinations may be a part of management and that CRC patients who develop COVID-19 infection may warrant closer follow-up during treatment.
EDRN PI Authors
Medline Author List
- Qureshi I
- Rella S
- Shaukat A
PubMed ID
Sources
- Cancer Data Expo