Aliases

• BTE-binding protein 2
• BTEB2
• Basic transcription element-binding protein 2
• CKLF
• Colon krueppel-like factor
• GC box binding protein 2
• GC-box-binding protein 2
• IKLF
• Intestinal-enriched krueppel-like factor
• KLF5
• Krueppel-like factor 5
• Kruppel-like factor 5 (intestinal)
• Transcription factor BTEB2
• basic transcription element binding protein 2
• basic transcription element-binding protein 2
• colon krueppel-like factor
• colon kruppel-like factor
• intestinal-enriched krueppel-like factor
• intestinal-enriched kruppel-like factor
• transcription factor BTEB2

Description

From NCBI Gene: This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

Attributes

QA State

Under Review

Type

Gene

HGNC Name

KLF5