LCP2
- Aliases
-
- 76 kDa tyrosine phosphoprotein
- LCP2
- SH2 domain-containing leukocyte protein of 76 kDa
- SH2 domain-containing leukocyte protein of 76kD
- SLP-76
- SLP-76 tyrosine phosphoprotein
- SLP76
- lymphocyte cytosolic protein 2
- lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
- lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD)
- Description
- LCP2, previously known as SLP76, functions as an adaptor or scaffolding protein. LCP2 has three modular domains. The amino-terminal end has an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. LCP2 also contains a central proline-rich domain and a COOH-terminal SH2 domain.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- LCP2
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.