MIF
- Aliases
-
- GIF
- GLIF
- Glycosylation-inhibiting factor
- L-dopachrome isomerase
- L-dopachrome tautomerase
- MIF
- MMIF
- macrophage migration inhibitory factor
- macrophage migration inhibitory factor (glycosylation-inhibiting factor)
- phenylpyruvate tautomerase
- Description
- MIF, a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation, plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. MIF is also closely related to tumorigenesis.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- MIF
- Certifications
-
- None
- QA State for Lung
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Certifications
-
- None
- QA State for Ovary
- Curated
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer.
- Diagnostic markers for early detection of ovarian cancer.
- Lung cancer diagnosis from proteomic analysis of preinvasive lesions.
- Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens.
- The state of molecular biomarkers for the early detection of lung cancer.
- Entrez Protein Reference Sequence for macrophage migration inhibitory factor [Homo sapiens]
- HGNC entry for macrophage migration inhibitory factor (glycosylation-inhibiting factor) MIF
- KEGG entry 4282 for human macrophage migration inhibitory factor (glycosylation-inhibiting factor) MIF
- UniProtKB/Swiss-Prot entry P14174 for MIF_HUMAN
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.