PCCA
- Aliases
-
- EC 6.4.1.3
- PCCA
- PCCase alpha subunit
- PCCase subunit alpha
- Propanoyl-CoA:carbon dioxide ligase subunit alpha
- pccA complementation group
- propanoyl-CoA:carbon dioxide ligase alpha subunit
- propionyl CoA carboxylase, alpha polypeptide
- propionyl Coenzyme A carboxylase, alpha polypeptide
- propionyl-CoA carboxylase alpha chain, mitochondrial
- Description
- PCCA, or propionyl CoA carboxylase, alpha polypeptide, is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. The beta subunit is PCCB. The enzyme deficiency propionic acidemia results from mutations in either PCCA or PCCB. Several isoforms for this gene have been identified, coded by multiple transcript variants.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- PCCA
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.