RBBP4
- Aliases
-
- CAF-1 subunit C
- CAF-I 48 kDa subunit
- CAF-I p48
- Chromatin assembly factor 1 subunit C
- Chromatin assembly factor I p48 subunit
- MSI1 protein homolog
- NURF55
- Nucleosome-remodeling factor subunit RBAP48
- RBAP48
- RBBP-4
- RBBP4
- RbAp48
- Retinoblastoma-binding protein 4
- Retinoblastoma-binding protein p48
- chromatin assembly factor 1 subunit C
- chromatin assembly factor I p48 subunit
- chromatin assembly factor/CAF-1 p48 subunit
- histone-binding protein RBBP4
- nucleosome-remodeling factor subunit RBAP48
- retinoblastoma binding protein 4
- retinoblastoma-binding protein 4
- retinoblastoma-binding protein p48
- Description
- From NCBI Gene: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Attributes
- QA State
- Under Review
- Type
- Gene
- HGNC Name
- RBBP4
- Certifications
-
- None
- QA State for Prostate
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.