TRIM22
- Aliases
-
- 50 kDa-stimulated trans-acting factor
- E3 ubiquitin-protein ligase TRIM22
- EC 6.3.2.-
- GPSTAF50
- RING finger protein 94
- RNF94
- STAF50
- Staf-50
- TRIM22
- Tripartite motif-containing protein 22
- staf-50
- stimulated trans-acting factor (50 kDa)
- tripartite binding motif 22
- tripartite motif containing 22
- tripartite motif protein TRIM22
- tripartite motif-containing 22
- tripartite motif-containing protein 22
- Description
- From NCBI Gene: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
Attributes
- QA State
- Curated
- Type
- Gene
- HGNC Name
- TRIM22
- Certifications
-
- None
- QA State for Prostate
- Curated
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.