TSPO
- Aliases
-
- BPBS
- BZRP
- DBI
- IBP
- MBR
- Mitochondrial benzodiazepine receptor
- PBR
- PBRS
- PBS
- PKBS
- PTBR
- Peripheral-type benzodiazepine receptor
- TSPO
- benzodiazapine receptor (peripheral)
- benzodiazepine peripheral binding site
- mDRC
- mitochondrial benzodiazepine receptor
- peripheral-type benzodiazepine receptor
- pk18
- translocator protein
- translocator protein (18kDa)
- Description
- TSPO is a conserved protein found at the outer mitochondrial membrane. TSPO interacts with some benzodiazepines and isoquinoline carboxamides and has different affinities than its endogenous counterpart. TSPO is also involved in the transport of porphyrins and heme.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- TSPO
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
- The 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migration.
- Translocator protein (TSPO) in breast cancer.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.