Abbreviated Name

BLADDER-PRE-VAL

Lead Investigator

Cairns, Paul — Fox Chase Cancer Center

Coordinating Investigator

Zheng, Yingye — Fred Hutchinson Cancer Center

Involved Investigators

• Kibel, Adam — Brigham and Womens Hospital
• Wei, John — University of Michigan Recruiting
• Wagner, Andrew — Beth Israel Deaconess Medical Center
• Sidransky, David — Johns Hopkins University
• Leach, Robin J — University of Texas Health Science Center at San Antonio
• Srivastava, Sudhir — National Cancer Institute
• Czerniak, Bogdan — The University of Texas MD Anderson Cancer Center
• Schoenberg, Mark P. — Johns Hopkins University
• Cairns, Paul — Fox Chase Cancer Center
• Sanda, Martin — Emory University
• Zheng, Yingye — Fred Hutchinson Cancer Center

Abstract

Study never Launched

Aims

This study will test the sensitivity of gene methylation in the presence of clinically evident, pathologically confirmed bladder cancer. This study will test the specificity of gene methylation in two groups of participants without bladder cancer - requiring cystoscopy for hematuria and for foreign body (urinary stones, stents, and catheters) or infection.

Analytic Method

Quantitative real time methylation specific PCR (qMSP) of urine sediment DNA using a panel of several methylated gene markers.

Outcome

Study never Launched

Publications

• No publications available at this time for this protocol.

Biomarkers

• No biomarkers available at this time for this protocol.

Data Collections

• No data collections available at this time for this protocol.

Start Date

Feb 1 2008

Estimated Finish Date

Feb 1 2009

Finish Date

May 1 2010

Protocol ID

226

Protocol Type

Collaboration

Fields of Research

• Hypermethylation

Collaborative Group

Prostate and Urologic Cancers Research Group

Cancer Types

• Malignant neoplasm of bladder

Phased Status

1