LTP2 Results Analysis Lenburg BU 2024

Abbreviated Name
LTP2 Results Analysis Lenburg BU 2024
Lead Investigator
Lenburg, Marc — Boston University
Coordinating Investigator
Zheng, Yingye — Fred Hutchinson Cancer Center
Involved Investigators

Abstract

Airway gene-expression biomarker Total RNA and genomic DNA will be isolated from bronchial airway brushings and nasal brushings. After controlling for RNA quality, quantity, and purity, 100ng of RNA will be used for genome-wide gene expression profiling via total RNA-sequencing. After controlling for DNA quality, quantity, and purity, 50 - 300 ng of DNA will be made available to investigators at the University of Toledo

Aims

Airway gene-expression biomarker Total RNA and genomic DNA will be isolated from bronchial airway brushings and nasal brushings. After controlling for RNA quality, quantity, and purity, 100ng of RNA will be used for genome-wide gene expression profiling via total RNA-sequencing. After controlling for DNA quality, quantity, and purity, 50 - 300 ng of DNA will be made available to investigators at the University of Toledo

Analytic Method

See LTP2 protocol

Outcome

Airway gene-expression biomarker Total RNA and genomic DNA will be isolated from bronchial airway brushings and nasal brushings. After controlling for RNA quality, quantity, and purity, 100ng of RNA will be used for genome-wide gene expression profiling via total RNA-sequencing. After controlling for DNA quality, quantity, and purity, 50 - 300 ng of DNA will be made available to investigators at the University of Toledo

Publications

  • No publications available at this time for this protocol.

Biomarkers

  • No biomarkers available at this time for this protocol.

Data Collections

  • No data collections available at this time for this protocol.
Start Date
Sep 12 2024
Estimated Finish Date
Mar 12 2025
Finish Date
Feb 15 2025
Protocol ID
551
Protocol Type
Reference Set
Fields of Research
  • Genomics
Collaborative Group
Lung and Upper Aerodigestive Cancers Research Group
Cancer Types
  • Malignant neoplasm of bronchus and lung
Phased Status
2

Associated Forms