Multimodal and Generative AI for Pathology
Faisal Mahmood, PhD
Harvard Medical School
Advances in digital pathology and artificial intelligence have presented the potential to build assistive tools for objective diagnosis, prognosis and therapeutic-response and resistance prediction. In this talk we will discuss our work on: (1) Data-efficient methods for weakly-supervised whole slide classification with examples in cancer diagnosis and subtyping (Nature BME, 2021), identifying origins for cancers of unknown primary (Nature, 2021) and allograft rejection (Nature Medicine, 2022) (2) Discovering integrative histology-genomic prognostic markers via interpretable multimodal deep learning (Cancer Cell, 2022; IEEE TMI, 2020; ICCV, 2021; CVPR, 2024; ICML, 2024). (3) Building unimodal and multimodal foundation models for pathology, contrasting with language and genomics (Nature Medicine, 2024a, Nature Medicine 2024b, CVPR 2024). (4) Developing a universal multimodal generative co-pilot and chatbot for pathology (Nature, 2024). (5) 3D Computational Pathology (Cell, 2024) (6) Bias and fairness in computational pathology algorithms (Nature Medicine, 2024).