Herman, James

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Indeterminate pulmonary nodule biomarker clinical utility trial Leading 0 0
LTP2 Analysis-Imaging-Herman Pittsburgh (2023) Leading 0 0
Validation of Molecular Biomarkers for the Early Detection of Lung Cancer in the setting of Indeterminate Pulmonary Nodules (Lung Team Project #2) Involved 15 0

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
LTP2 Results Analysis-Herman-UPittsburgh 2024 Leading 0 0

Publications

Publication NamePubMed IDJournal
A sample-to-answer droplet magnetofluidic assay platform for quantitative methylation-specific PCR. 29594810 Biomed Microdevices
Cancer Methylation Biomarker Detection in an Automated, Portable, Multichannel Magnetofluidic Platform. 38669469 ACS Nano
Detection of Promoter DNA Methylation in Urine and Plasma Aids the Detection of Non-Small Cell Lung Cancer. 32430478 Clin Cancer Res
DNA-methylation for the detection and distinction of 19 human malignancies. 33666134 Epigenetics
Droplet Magnetofluidic Assay Platform for Quantitative Methylation-Specific PCR. 35094330 Methods Mol Biol
Fabrication of Multilayer Microfluidic Arrays for Passive, Efficient DNA Trapping and Profiling. 37300626 Methods Mol Biol
Facile profiling of molecular heterogeneity by microfluidic digital melt. 30263958 Sci Adv
High-throughput sample processing for methylation analysis in an automated, enclosed environment. 35058199 SLAS Technol
Highly Efficient Real-Time Droplet Analysis Platform for High-Throughput Interrogation of DNA Sequences by Melt. 31356737 Anal Chem
Leveraging locus-specific epigenetic heterogeneity to improve the performance of blood-based DNA methylation biomarkers. 33081832 Clin Epigenetics
Ligation-Enabled Fluorescence-Coding PCR for High-Dimensional Fluorescence-Based Nucleic Acid Detection. 33427441 Anal Chem
Multilayer microfluidic array for highly efficient sample loading and digital melt analysis of DNA methylation. 30623957 Lab Chip
Multiplex Digital Methylation-Specific PCR for Noninvasive Screening of Lung Cancer. 37039321 Adv Sci (Weinh)
Multiplex digital profiling of DNA methylation heterogeneity for sensitive and cost-effective cancer detection in low-volume liquid biopsies. 39576863 Sci Adv
Noninvasive Diagnostics for Early Detection of Lung Cancer: Challenges and Potential with a Focus on Changes in DNA Methylation. 33148791 Cancer Epidemiol Biomarkers Prev
Postoperative Lymph Is a Proximal Source of ctDNA for Detection of Recurrence in HPV-Independent Head and Neck Cancer. 41182409 Clin Cancer Res
Proof of concept: Detection of cell free RNA from EDTA plasma in patients with lung cancer and non-cancer patients. 37182637 Clin Biochem
Streptococcus pneumoniae promotes lung cancer development and progression. 36685035 iScience
Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules. 32138766 Clin Epigenetics
Utilizing MiSeq Sequencing to Detect Circulating microRNAs in Plasma for Improved Lung Cancer Diagnosis. 37373422 Int J Mol Sci

Interests

Use of DNA methylation detection for diagnosis, early detection, and MRD
Use of DNA methylation detection for diagnosis, early detection, and MRD

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Photograph of Herman, James
Site
University of Pittsburgh School of Medicine
Degree(s)
M.D.
Email
hermanj3@upmc.edu
Person ID
3730
Note
To update contact information, please visit the Data Management and Coordinating Center .