CA72-4

Aliases
  • CA72-4
  • Cancer-associated Antigen 72-4
  • TAG-72
  • tumor-associated glycoprotein 72
Description
High-MW mucin-type glycoprotein expressed on epithelial cancer cells.
Attributes
QA State
Accepted
Type
Protein
HGNC Name
Certifications
  • None
QA State for Breast
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

Certifications
  • None
QA State for Ovary
Accepted
Organ-Specific Notes

Overexpression (protein) studies in ovarian cancer.

Performance Comment

Of the 28 ovarian cancer biomarkers tested in prediagnostic specimens, from the PLCO, CA125 remains the the single best biomarker for ovarian cancer and has its strongest signal within six months of diagnosis. CA72-4 alone was not a strong predictor.

Supporting Study Data
PLCO Ovarian Phase III Validation Study
Study phase on the ovary: 3

see objectives

View Protocol
Decision rule: PMID:21372037
SPORE/EDRN/PRE-PLCO Ovarian Phase II Validation Study
Study phase on the ovary: 3

see objectives

View Protocol
Decision rule: PMID:21372037
Ovary-Specific Protocols
  • No organ-level protocols specified for ovary.
Ovary-Specific Publications
  • No organ-level publications were listed for ovary.
Ovary-Specific Resources
  • No organ-level resources were given for ovary.
  • No resources were specified for this biomarker.