PTPRC
- Aliases
-
- B220
- CD45
- CD45 antigen
- CD45R
- EC 3.1.3.48
- GP180
- L-CA
- LCA
- LY5
- Leukocyte common antigen
- PTPRC
- T200
- T200 glycoprotein
- T200 leukocyte common antigen
- protein tyrosine phosphatase, receptor type, C
- protein tyrosine phosphatase, receptor type, c polypeptide
- receptor-type tyrosine-protein phosphatase C
- Description
- PTPRC is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. PTPRC is required for T-cell activation through the antigen receptor. PTPRC contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and is classified as a receptor type PTP.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- PTPRC
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.