Aliases

• 80kDa
• 86 KDa Subunit Of Ku Antigen
• ATP-Dependent DNA Helicase 2 Subunit 2
• ATP-Dependent DNA Helicase II 80 KDa Subunit
• CTC Box-Binding Factor 85 KDa Subunit
• CTC85
• CTCBF
• DNA Repair Protein XRCC5
• EC 3.6.4.-
• G22P2
• KARP-1
• KARP1
• KU80
• KUB2
• Ku Autoantigen
• Ku Autoantigen, 80kDa
• Ku80
• Ku86
• Ku86 Autoantigen Related Protein 1
• Lupus Ku Autoantigen Protein P86
• NFIV
• Nuclear Factor IV
• TLAA
• Thyroid-Lupus Autoantigen
• X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining)
• X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining; Ku Autoantigen, 80kD)
• X-Ray Repair Cross-Complementing Protein 5
• XRCC5

Description

From NCBI Entrez Gene: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Attributes

QA State

Curated

Type

Protein

HGNC Name

XRCC5