Abbreviated Name

BRS-I

Lead Investigator

Marks, Jeffrey — Duke University Medical Center

Coordinating Investigator

Zheng, Yingye — Fred Hutchinson Cancer Center

Involved Investigators

• Crichton, Dan — NASA Jet Propulsion Laboratory
• Heine, John — H. Lee Moffitt Cancer Center & Research Institute, Inc.
• Lokshin, Anna — University of Pittsburgh Cancer Institute
• Tang, Cha-Mei — Creatv MicroTech Inc.
• Anderson, Karen — Arizona State University
• Marks, Jeffrey — Duke University Medical Center
• Diaz-Mayoral, Norma — Frederick National Laboratory for Cancer Research
• Srivastava, Sudhir — National Cancer Institute
• Esserman, Laura J. — University of California at San Francisco
• Engstrom, Paul — Fox Chase Cancer Center
• Zheng, Yingye — Fred Hutchinson Cancer Center

Abstract

The primary objective of this study is to assemble a well-characterized set of blood specimens and images to test biomarkers that, in conjunction with mammography, can detect and discriminate breast cancer. These samples will be divided to provide “sets” of specimens that can be tested in a number of different laboratories. Since tests will be performed on the same sets of samples, the data will be directly comparable and decisions regarding which biomarker or set of biomarkers have value in breast cancer detection can be made. These sets will reside at a National Cancer Institute facility at Frederick, MD.

Aims

see Objectives

Analytic Method

N/A

Outcome

The primary objective of this study is to assemble a well-characterized set of blood specimens and images to test biomarkers that, in conjunction with mammography, can detect and discriminate breast cancer. These samples will be divided to provide “sets” of specimens that can be tested in a number of different laboratories. Since tests will be performed on the same sets of samples, the data will be directly comparable and decisions regarding which biomarker or set of biomarkers have value in breast cancer detection can be made. These sets will reside at a National Cancer Institute facility at Frederick, MD.

Publications

• Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.

Biomarkers

• No biomarkers available at this time for this protocol.

Data Collections

There are 3 collections of data that have not yet been made public. Logging in may you give you access to the names of the non-public data collections.

 Team Project

Start Date

Jun 2 2006

Estimated Finish Date

Mar 31 2021

Protocol ID

121

Protocol Type

Reference Set

Fields of Research

• Other

Collaborative Group

Breast and Gynecologic Cancers Research Group

Cancer Types

• Malignant neoplasm of breast