Abbreviated Name

BDL Colon Biomarker Development

Lead Investigator

Markowitz, Sanford — Case Western Reserve University

Coordinating Investigator

Markowitz, Sanford — Case Western Reserve University

Involved Investigators

• Markowitz, Sanford — Case Western Reserve University

Abstract

Prospective enrollment of individuals undergoing stool DNA testing versus colonoscopy with follow-up colonoscopy at 1 year of individuals with persistently positive stool DNA performed to evaluate sensitivity of stool DNA.

Aims

Evaluate methylated stoo DNA for early detection colorectal cancer

Analytic Method

No analytic method available.

Publications

• Evaluation of Patients with an Apparent False Positive Stool DNA Test: The Role of Repeat Stool DNA Testing.
• Performance of multitarget stool DNA testing in African American patients.

Biomarkers

• Vimentin methylation (Colosure)

Data Collections

• No data collections available at this time for this protocol.

 Team Project

Start Date

Jan 1 2010

Estimated Finish Date

Jan 1 2018

Protocol ID

487

Protocol Type

Single

Fields of Research

• Epigenomics

Collaborative Group

G.I. and Other Associated Cancers Research Group

Cancer Types

• Malignant neoplasm of colon