Bigbee, William L.
Open Protocols
| Protocol Name | Investigatory Role | Biomarkers | Data Collections |
|---|---|---|---|
| Collaborative study on SELDI biomarker discovery and serum protein profiling of lung cancers | Involved | 0 | 0 |
| EDRN Informatics Pilot Project | Leading | 0 | 0 |
Closed Protocols
| Protocol Name | Investigatory Role | Biomarkers | Data Collections |
|---|---|---|---|
| Autoantibody Approach for Serum-Based Detection of Head and Neck Cancer | Involved | 8 | 0 |
| EDRN Resource Network Exchange | Involved | 0 | 0 |
| EDRN-WHI Pre-Clinical Colon Ca Specimens | Involved | 0 | 1 |
| Proteomic Approach for Diagnostic Applications in Head and Neck Cancer | Involved | 0 | 0 |
| Proteomic Profiling of Serum and Other Body Fluids for the Early Detection of Colon Cancers | Involved | 0 | 0 |
| SELDI Phase I: Assay Validation-Prostate | Involved | 1 | 1 |
| SELDI Validation Study Phase II | Involved | 1 | 1 |
| Standard Specimen Reference Set: Lung | Leading | 0 | 0 |
Publications
Interests
- Research Interests
- Dr. Bigbee’s research activities are focused on the development and validation of cancer early detection and diagnostic molecular markers for application in cancer molecular epidemiology population-based screening and clinical research studies. To facilitate this translational cancer research, Dr. Bigbee is appointed as a Staff Investigator and Director of the Clinical Proteomics Facility in the University of Pittsburgh Cancer Institute (UPCI) and maintains related UPCI programmatic appointments as Leader, Molecular Biomarkers Group, Cancer Epidemiology Program, and as a member of the Head and Neck, and Lung and Thoracic Malignancies Programs. His research expertise is centered in clinical proteomics with EDRN, SPORE and additional NCI/DoD funding support to assess the diagnostic performance of lung cancer-specific protein expression profiles in serum and the use of MALDI-TOF and related mass spectrometry technologies for serum protein expression profiling analysis for early detection of breast, endometrial, head & neck, ovarian, pancreatic, and prostate cancer. Lastly, Dr. Bigbee is the Director of the UPCI Clinical Proteomics Facility, a new UPCI-supported shared resource focused on the development and application of proteomic profiling technology, including Luminex Multianalyte Profiling (LabMAP) for cancer early detection and screening and molecular diagnosis, prognosis, and classification of human tumors.
To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.
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- Site
- University of Pittsburgh Cancer Institute
- Degree(s)
- Ph.D.
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bigbeewl@upmc.edu - Fax
- 412-641-2458
- Person ID
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997 - EDRN Title
- EDRN Associate Member
- Note
- To update contact information, please visit the Data Management and Coordinating Center .
