Abbreviated Name

PaCa Bake Off 2

Lead Investigator

Brand, Randall E. — University of Pittsburgh

Coordinating Investigator

Zheng, Yingye — Fred Hutchinson Cancer Center

Involved Investigators

• Lokshin, Anna — University of Pittsburgh Cancer Institute
• Batra, Surinder — University of Nebraska Medical Center
• Lampe, Paul — Fred Hutchinson Cancer Center
• Haab, Brian — Van Andel Research Institute
• Brand, Randall E. — University of Pittsburgh
• Hanash, Samir — The University of Texas MD Anderson Cancer Center
• Maitra, Anirban — NYU Langone Health
• Srivastava, Sudhir — National Cancer Institute
• Zheng, Yingye — Fred Hutchinson Cancer Center

Abstract

No abstract availalbe.

Aims

Specific Aim 1. Validate the biomarkers that performed well in the first team project. Specific Aim 2. Optimize biomarkers from the first team project and test for improvements over prior performance. Specific Aim 3. Test the novel combination-markers that were suggested by the first team project.

Analytic Method

sTRA assay immobilized antibody to capture a protein or glycan.

Comments

No comments available.

Outcome

See manuscript

Secure Outcome

No secure outcome available.

Publications

• A rigorous multi-laboratory study of known PDAC biomarkers identifies increased sensitivity and specificity over CA19-9 alone.

Biomarkers

• CA19-9
• CA199:sTRA
• MUC5AC:sTRA
• sTRA

Data Collections

• No data collections available at this time for this protocol.

Start Date

Sep 1 2018

Finish Date

Nov 1 2024

Protocol ID

450

Protocol Type

Collaboration

Fields of Research

• Glycomics
• Proteomics

Collaborative Group

G.I. and Other Associated Cancers Research Group

Cancer Types

• Malignant neoplasm of pancreas

Phased Status

2